Pressure-distension relationship in arteries and arterioles in response to 5 wk of horizontal bedrest | Canada Hyperbarics Skip to main content
Study Am J Physiol Heart Circ Physiol 2008

Pressure-distension relationship in arteries and arterioles in response to 5 wk of horizontal bedrest

Eiken O, Kölegård R, Mekjavic I — Am J Physiol Heart Circ Physiol, 2008

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers studied how five weeks of horizontal bedrest affected the ability of arteries and arterioles to expand in response to pressure in ten subjects.

What They Found

After five weeks of bedrest, the distension of the tibial artery in the leg increased threefold, from 8% to 24%, and the brachial artery in the arm increased by one-third, from 15% to 20%. Blood flow in the tibial artery also showed a greater increase after bedrest (50 ml/min) compared to before (13 ml/min) when pressure was applied.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

A limitation of this study is its small sample size of only ten male subjects, which may limit the generalizability of the findings.

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Study Details

Study Type Study
Category Uncategorised
Source Pubmed
PubMed ID 18660441
Year Published 2008
Journal Am J Physiol Heart Circ Physiol
MeSH Terms Adolescent; Adult; Arteries; Arterioles; Bed Rest; Blood Pressure; Electrocardiography; Forearm; Heart Rate; Humans; Hypotension, Orthostatic; Leg; Male; Recovery of Function; Regional Blood Flow; Vascular Resistance

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.