Pretreatment with hyperbaric oxygen and its effect on neuropsychometric dysfunction and systemic inflammatory response after cardiopulmonary bypass: a prospective randomized double-blind trial. | Canada Hyperbarics Skip to main content
RCT The Journal of thoracic and cardiovascular surgery 2005

Pretreatment with hyperbaric oxygen and its effect on neuropsychometric dysfunction and systemic inflammatory response after cardiopulmonary bypass: a prospective randomized double-blind trial.

Alex J, Laden G, Cale AR, Bennett S, Flowers K, Madden L, et al. — The Journal of thoracic and cardiovascular surgery, 2005

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a prospective randomized double-blind trial to evaluate if pretreatment with hyperbaric oxygen affects neuropsychometric dysfunction and systemic inflammation in 64 patients undergoing coronary artery bypass grafting.

What They Found

The abstract indicates that the control group (Group A, n=31) experienced a significant postoperative increase in certain inflammatory markers. However, the abstract provided does not detail the comparative findings for the hyperbaric oxygen group (Group B, n=33) regarding neuropsychometric dysfunction or the full systemic inflammatory response.

What This Means for Canadian Patients

Without the complete study results, it is not possible to determine the practical implications of hyperbaric oxygen pretreatment for Canadian patients undergoing cardiopulmonary bypass. If future research confirms a benefit, this therapy could potentially reduce postoperative complications.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor does it involve Canadian researchers or patients.

Study Limitations

A significant limitation is that the provided abstract is incomplete, preventing a full understanding of the study's primary findings regarding neuropsychometric dysfunction and the comparative effects on inflammatory markers.

Was this summary helpful?

Study Details

Study Type RCT
Category Wound Care
Source Pubmed
PubMed ID 16308008
Year Published 2005
Journal The Journal of thoracic and cardiovascular surgery
MeSH Terms Aged; Brain Diseases; Cardiopulmonary Bypass; Double-Blind Method; Female; Humans; Hyperbaric Oxygenation; Inflammation; Male; Neuropsychological Tests; Preoperative Care; Prospective Studies

Cite This Study

Share

Find a Canadian Clinic Treating Wound Care

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.