What Researchers Did
Researchers described one of the earliest reported uses of recombinant human platelet-derived growth factor-BB (rhPDGF) gel to improve the healing of a previously irradiated, refractory dermal wound on the neck that had persisted for 12 years.
What They Found
A 47-year-old man with a 12-year history of a non-healing neck wound following radiation therapy received topical rhPDGF gel treatment. After 6 months, sufficient granulation tissue developed, enabling a successful split-thickness skin graft, and the patient's continuous pain resolved.
Canadian Relevance
This study has no direct Canadian connection as it was conducted outside of Canada and did not involve Canadian researchers or patients.
Study Limitations
As a single case report, this study's findings cannot be generalized to a wider patient population and require further investigation through larger clinical trials.