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Review J Reprod Immunol 2017

Pulmonary hypertension associated with bronchopulmonary dysplasia in preterm infants

Bui C, Pang M, Sehgal A, Theda C, Lao J, Berger P, et al. — J Reprod Immunol, 2017

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This systematic review discussed the current understanding of bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) in preterm infants and highlighted potential new ways to predict and treat the condition.

What They Found

The researchers found that bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) affects 17-24% of infants with bronchopulmonary dysplasia (BPD). BPD-PH significantly increases the risk of illness and death, with mortality rates reaching up to 50% in affected infants. Currently, there is no safe and effective treatment for BPD and BPD-PH.

What This Means for Canadian Patients

This study highlights the severe health challenges faced by preterm infants with BPD-PH, a condition that significantly increases their risk of illness and death. For Canadian families, this means that preterm infants with BPD-PH face a serious condition with limited treatment options, underscoring the need for better diagnostic tools and therapies. The review's focus on emerging biomarkers could eventually lead to earlier identification and improved care strategies for these vulnerable infants in Canada.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a review, this study synthesizes existing research and does not present new experimental data or clinical trial results.

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Study Details

Study Type Review
Category Systematic Reviews
Source Pubmed
PubMed ID 29035757
Year Published 2017
Journal J Reprod Immunol
MeSH Terms Animals; Bronchopulmonary Dysplasia; Fetal Development; Humans; Hyperbaric Oxygenation; Hypertension, Pulmonary; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Inflammation; Premature Birth; Respiration; Vascular Remodeling

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.