Radiation-induced cystitis treated with hyperbaric oxygen therapy (RICH-ART): a randomised, controlled, phase 2–3 trial | Canada Hyperbarics Skip to main content
RCT Lancet Oncol 2019

Radiation-induced cystitis treated with hyperbaric oxygen therapy (RICH-ART): a randomised, controlled, phase 2–3 trial

Oscarsson N, Arnell P, Lodding P, et al. — Lancet Oncol, 2019

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomized controlled trial across five Nordic hospitals to determine if hyperbaric oxygen therapy could reduce symptoms of late radiation cystitis.

What They Found

The provided abstract describes the study's design and aims to assess if hyperbaric oxygen therapy could mitigate symptoms of late radiation cystitis. However, specific findings, numbers, or percentages from the trial's outcomes were not included in the provided abstract.

What This Means for Canadian Patients

If proven effective, hyperbaric oxygen therapy could offer a valuable treatment option for Canadian patients experiencing late radiation cystitis following pelvic radiotherapy. This could potentially improve quality of life for individuals suffering from this debilitating side effect of cancer treatment.

Canadian Relevance

This study investigates a condition, late radiation cystitis, which falls under Health Canada's recognized indication for hyperbaric oxygen therapy: 'Delayed Radiation Injury (Soft Tissue and Bone Necrosis)'.

Study Limitations

A key limitation of this study is that no masking was applied, which could introduce bias.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type RCT
Category Radiation Injury
Source Pubmed
PubMed ID 31537473
Year Published 2019
Journal Lancet Oncol

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology