Randomised phase II trial of hyperbaric oxygen therapy in patients with chronic arm lymphoedema after radiotherapy for cancer. | Canada Hyperbarics Skip to main content
RCT Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010

Randomised phase II trial of hyperbaric oxygen therapy in patients with chronic arm lymphoedema after radiotherapy for cancer.

Gothard L, Haviland J, Bryson P, Laden G, Glover M, Harrison S, et al. — Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a randomised phase II trial to evaluate hyperbaric oxygen therapy in patients with chronic arm lymphoedema following radiotherapy for cancer.

What They Found

At 12 months, the median ipsilateral limb volume was 131.2% in the control group and 133.5% in the hyperbaric oxygen therapy group, relative to the contralateral limb. The study found no evidence of a beneficial effect of hyperbaric oxygen therapy on arm lymphoedema or secondary endpoints.

What This Means for Canadian Patients

Canadian patients with chronic arm lymphoedema after cancer radiotherapy should be aware that hyperbaric oxygen therapy did not demonstrate a beneficial effect in this study. Therefore, current standard care remains the recommended approach for managing this condition.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The relatively small sample size of this phase II trial limits the generalizability of the findings.

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Study Details

Study Type RCT
Category Radiation Injury
Source Pubmed
PubMed ID 20605648
Year Published 2010
Journal Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
MeSH Terms Arm; Breast Neoplasms; Chronic Disease; Endpoint Determination; Female; Humans; Hyperbaric Oxygenation; Lymph Nodes; Lymphedema; Middle Aged; Quality of Life; Radionuclide Imaging; Risk Factors; Statistics, Nonparametric; Surveys and Questionnaires

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.