Randomized controlled trial of topical hyperbaric oxygen for treatment of diabetic foot ulcers. | Canada Hyperbarics Skip to main content
RCT Diabetes care 1988

Randomized controlled trial of topical hyperbaric oxygen for treatment of diabetic foot ulcers.

Leslie CA, Sapico FL, Ginunas VJ, Adkins RH — Diabetes care, 1988

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a randomized controlled trial to evaluate the effect of two weeks of topical hyperbaric oxygen on diabetic foot ulcers in 28 patients.

What They Found

Both the topical hyperbaric oxygen group (12 patients) and the control group (16 patients) showed significant reductions in ulcer area and depth over 14 days. However, there was no statistically significant difference in ulcer size changes or microbial counts between the two treatment groups.

What This Means for Canadian Patients

Canadian patients with diabetic foot ulcers may not benefit from topical hyperbaric oxygen therapy as a primary treatment based on these findings. Standard wound care approaches appear to be similarly effective for ulcer size reduction.

Canadian Relevance

This study was not conducted in Canada and has no direct Canadian connection.

Study Limitations

The study's small sample size of 28 patients and short two-week treatment duration limit the generalizability of its findings.

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Study Details

Study Type RCT
Category Wound Care
Source Pubmed
PubMed ID 3289861
Year Published 1988
Journal Diabetes care
MeSH Terms Bacteria; Bacterial Infections; Candidiasis; Clinical Trials as Topic; Diabetic Neuropathies; Female; Humans; Hyperbaric Oxygenation; Leg Ulcer; Male; Middle Aged; Random Allocation

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.