Rapid Progression of Cutaneous Large B-Cell Lymphoma During Hyperbaric Oxygen Therapy: A Case Report | Canada Hyperbarics Skip to main content
Case Report Undersea Hyperb Med 2025

Rapid Progression of Cutaneous Large B-Cell Lymphoma During Hyperbaric Oxygen Therapy: A Case Report

Kelly M, Jones E, Shapshak D — Undersea Hyperb Med, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case report detailing a patient with cutaneous B-cell lymphoma who experienced rapid disease progression during hyperbaric oxygen therapy.

What They Found

They found that a patient with cutaneous B-cell lymphoma and non-healing ulcerations, who began hyperbaric oxygen (HBO₂) therapy, experienced worsening wounds shortly after treatment initiation. Subsequent biopsies confirmed rapid progression to cutaneous large B-cell lymphoma, leading to HBO₂ discontinuation and aggressive chemotherapy.

What This Means for Canadian Patients

Canadian patients with a history of cutaneous B-cell lymphoma who are considering or undergoing hyperbaric oxygen therapy should be closely monitored for any signs of tumor recurrence or disease worsening. Early detection of such changes is crucial to promptly adjust treatment strategies and prevent rapid disease progression.

Canadian Relevance

This specific case report has no direct Canadian connection.

Study Limitations

As a single case report, these findings may not be generalizable to all patients with cutaneous B-cell lymphoma undergoing hyperbaric oxygen therapy.

Was this summary helpful?

Study Details

Study Type Case Report
Category Wound Care
Source Pubmed
PubMed ID 41223397
Year Published 2025
Journal Undersea Hyperb Med
MeSH Terms Humans; Hyperbaric Oxygenation; Skin Neoplasms; Female; Lymphoma, Large B-Cell, Diffuse; Leukemia, Lymphocytic, Chronic, B-Cell; Disease Progression; Radiation Injuries; Middle Aged; Aged; Lymphoma, B-Cell

Cite This Study

Share

Find a Canadian Clinic Treating Wound Care

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.