What Researchers Did
Researchers investigated whether hyperbaric oxygen treatment (100% O2 at 2.8 bar) could make the antibiotic ciprofloxacin more effective against *Pseudomonas aeruginosa* biofilms grown in a lab setting.
What They Found
They discovered that reoxygenating the biofilms with HBOT significantly enhanced ciprofloxacin's ability to kill *P. aeruginosa*. This proof-of-principle study demonstrated that combining ciprofloxacin treatment with HBOT has the potential to improve the treatment of *P. aeruginosa* biofilm infections.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
This was a proof-of-principle study conducted in a lab using artificial biofilms, meaning further human studies are needed to confirm these effects.