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Clinical Study Annales francaises d'anesthesie et de reanimation 1994

Risks of hydrogen peroxide irrigation in military surgery.

Saïssy JM, Guignard B, Pats B, Lenoir B, Rouvier B — Annales francaises d'anesthesie et de reanimation, 1994

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported two cases of severe complications following hydrogen peroxide irrigation in war wounds.

What They Found

In both reported cases, patients experienced tachypnoea, major arterial desaturation, and a precordial "mill-wheel" murmur after hydrogen peroxide injection. One patient developed hemiplegia from paradoxical arterial gas embolism, while the other suffered pulmonary oedema. Both patients recovered after hyperbaric oxygen therapy.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a case report of only two patients, this study's findings are limited in generalizability and lack a comparative control group.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 7733529
Year Published 1994
Journal Annales francaises d'anesthesie et de reanimation
MeSH Terms Adult; Embolism, Air; Fractures, Open; France; Humans; Hydrogen Peroxide; Male; Military Medicine; Risk Factors; Subcutaneous Emphysema; Therapeutic Irrigation; Warfare; Wounds and Injuries

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology