Safety of hyperbaric oxygen therapy in patients... (2024 study) Skip to main content
Retrospective Study PloS one 2024 Canadian

Safety of hyperbaric oxygen therapy in patients with heart failure: A retrospective cohort study.

Schiavo S, Brenna CTA, Albertini L, Djaiani G, Marinov A, Katznelson R, PloS one, 2024

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Doctors reviewed medical charts of patients with heart failure who chose to have hyperbaric oxygen therapy (HBOT), to see whether it caused heart-related complications.

What They Found

This retrospective cohort study reviewed 23 patients with pre-existing heart failure who underwent elective HBOT at two Toronto-area hyperbaric centers, completing an average of 39 sessions (range 6-62) at either 2.0 ATA (11 patients) or 2.4 ATA (12 patients); only two patients received fewer than 10 sessions. Twenty-one of the 23 patients completed treatment without complications, but two patients, including one with reduced ejection fraction, developed symptoms consistent with HBOT-related heart failure exacerbation. Of the group, 13 patients had preserved ejection fraction (mean LVEF 55%), 7 had reduced ejection fraction (mean LVEF 35%) with some also having reduced right heart function, valve leakage, or high lung pressure, and 3 had mid-range ejection fraction (mean LVEF 44%). Nearly all patients were already being treated with diuretics or dialysis for fluid balance.

Canadian Relevance

This study was conducted in Canada, reviewing patients treated at two Toronto-area hyperbaric centers (Toronto General Hospital and Rouge Valley Hyperbaric Medical Centre).

Study Limitations

This was a small, retrospective chart review of only 23 patients at two centers with no control group, so it cannot prove that HBOT caused or did not cause the heart failure symptoms observed.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Retrospective Study
Category Cardiac
Source Pubmed
PubMed ID 38330042
Year Published 2024
Journal PloS one
MeSH Terms Male; Humans; Heart Failure; Stroke Volume; Ventricular Function, Left; Retrospective Studies; Hyperbaric Oxygenation; Pulmonary Edema; Prognosis; Ventricular Dysfunction, Left; Diuretics; Dyspnea

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology