Saturation Gap During Anesthesia in Glucose-6-Phosphate Dehydrogenase Deficiency and Methemoglobinemia: A Case Report and Review of Perioperative Management | Canada Hyperbarics Skip to main content
Case Report Cureus 2026

Saturation Gap During Anesthesia in Glucose-6-Phosphate Dehydrogenase Deficiency and Methemoglobinemia: A Case Report and Review of Perioperative Management

Santiago B, de Sousa G, Felippe V, Bersot G, Bersot C, Lessa M — Cureus, 2026

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on a 20-year-old man with G6PD deficiency and suspected methemoglobinemia undergoing an elective heart procedure.

What They Found

Despite a pulse oximetry reading of 45% oxygen saturation on room air, the patient's arterial blood gas showed a partial pressure of oxygen exceeding 400 mmHg, confirming adequate oxygenation. The patient underwent general anesthesia without complications, experiencing stable hemodynamics and no evidence of tissue hypoxia or hemolysis.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a single case report, the findings may not apply to all patients with G6PD deficiency and methemoglobinemia.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Case Report
Category Uncategorised
Source Pubmed
PubMed ID 41988351
Year Published 2026
Journal Cureus

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology