Short- and Long-Term Efficacy of Hyperbaric Oxygen Therapy in Irradiated Breast Cancer Patients With Long-Standing Lymphedema: A Prospective Case Series | Canada Hyperbarics Skip to main content
Case Report Cancer Rep (Hoboken) 2025

Short- and Long-Term Efficacy of Hyperbaric Oxygen Therapy in Irradiated Breast Cancer Patients With Long-Standing Lymphedema: A Prospective Case Series

Chitapanarux I, Chachvarat S, Sripan P, Pattarasakulchai T, Pattamapaspong N, Kanthawang T, et al. — Cancer Rep (Hoboken), 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a prospective case series to evaluate the short- and long-term efficacy of 30 sessions of hyperbaric oxygen therapy in six breast cancer patients with long-standing lymphedema.

What They Found

The study observed a decrease in arm volume and an improvement in functional assessment scores (Quick-DASH) at 3, 6, and 24 months following hyperbaric oxygen therapy. Six breast cancer patients with lymphedema, averaging 9 years since onset, participated in the treatment.

What This Means for Canadian Patients

Canadian breast cancer patients experiencing long-standing lymphedema might find hyperbaric oxygen therapy to be a beneficial treatment option for reducing arm swelling and improving arm function. This therapy could offer an alternative approach to manage persistent symptoms that have not responded to other interventions.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor did it involve Canadian researchers or patients.

Study Limitations

A significant limitation of this study is its small sample size of only six patients and the absence of a control group, which limits the generalizability and strength of the findings.

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Study Details

Study Type Case Report
Category Radiation Injury
Source Pubmed
PubMed ID 39778090
Year Published 2025
Journal Cancer Rep (Hoboken)
MeSH Terms Humans; Hyperbaric Oxygenation; Female; Prospective Studies; Middle Aged; Breast Neoplasms; Aged; Lymphedema; Treatment Outcome; Breast Cancer Lymphedema; Lymph Node Excision; Mastectomy; Adult; Time Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.