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Case Report Cancer Rep (Hoboken) 2025

Short- and Long-Term Efficacy of Hyperbaric Oxygen Therapy in Irradiated Breast Cancer Patients With Long-Standing Lymphedema: A Prospective Case Series

Chitapanarux I, Chachvarat S, Sripan P, Pattarasakulchai T, Pattamapaspong N, Kanthawang T, et al., Cancer Rep (Hoboken), 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers followed six breast cancer patients with long-standing arm swelling (lymphedema) to see how their arm size and arm function changed after hyperbaric oxygen therapy.

What They Found

This prospective case series of six patients found that arm volume and Quick-DASH function scores were lower at 3, 6, and 24 months after treatment compared to before treatment, but these changes were not statistically significant. Patients had lived with lymphedema for an average of 9 years (range 2 to 17 years) before starting treatment. All six received 30 sessions of hyperbaric oxygen at twice atmospheric pressure, 90 minutes per session, five days a week. Because the study only included six people and the changes did not reach statistical significance, the results cannot show whether hyperbaric oxygen caused any real improvement.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

With only six patients, no control group, and changes that were not statistically significant, this case series cannot establish whether hyperbaric oxygen therapy had any real effect on lymphedema.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Case Report
Category Radiation Injury
Source Pubmed
PubMed ID 39778090
Year Published 2025
Journal Cancer Rep (Hoboken)
MeSH Terms Humans; Hyperbaric Oxygenation; Female; Prospective Studies; Middle Aged; Breast Neoplasms; Aged; Lymphedema; Treatment Outcome; Breast Cancer Lymphedema; Lymph Node Excision; Mastectomy; Adult; Time Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology