Soluble ICAM-1 is modulated by hyperbaric oxygen treatment and correlates with disease severity and mortality in patients with necrotizing soft-tissue infection. | Canada Hyperbarics Skip to main content
Clinical Study Journal of applied physiology (Bethesda, Md. : 1985) 2021

Soluble ICAM-1 is modulated by hyperbaric oxygen treatment and correlates with disease severity and mortality in patients with necrotizing soft-tissue infection.

Hedetoft M, Moser C, Jensen PØ, Vinkel J, Hyldegaard O — Journal of applied physiology (Bethesda, Md. : 1985), 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated how hyperbaric oxygen treatment affects soluble ICAM-1 levels and their correlation with disease severity and mortality in patients with necrotizing soft-tissue infection.

What They Found

The study revealed that soluble ICAM-1 levels were modulated by hyperbaric oxygen treatment in patients with necrotizing soft-tissue infection. These levels significantly correlated with disease severity and mortality, providing numerical insights into their prognostic value.

What This Means for Canadian Patients

Understanding the role of soluble ICAM-1 and hyperbaric oxygen treatment could potentially lead to improved monitoring and therapeutic strategies for Canadian patients suffering from necrotizing soft-tissue infections. This research may help clinicians better assess disease severity and predict outcomes, guiding more effective patient management.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or with Canadian participants.

Study Limitations

A limitation of this study could be the need for larger, prospective trials to validate these findings across diverse patient populations.

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Study Details

Study Type Clinical Study
Category Infection
Source Pubmed
PubMed ID 33444122
Year Published 2021
Journal Journal of applied physiology (Bethesda, Md. : 1985)
MeSH Terms Humans; Hyperbaric Oxygenation; Intercellular Adhesion Molecule-1; Oxygen; Severity of Illness Index; Soft Tissue Infections

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.