What Researchers Did
Researchers presented a case report about a 17-year-old girl with cyclic neutropenia who developed osteonecrosis of the jaw after previously receiving zoledronate treatment.
What They Found
The patient presented with extreme mobility of several mandibular teeth, severe gingival recession, and exposed jaw bone, confirmed as bone sequestration by imaging. Conservative treatments, including antibiotic therapy, periodontal cleaning, and hyperbaric chamber treatment, were unsuccessful. The condition worsened, requiring surgical removal of the affected bone and teeth.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
As a single case report, the findings from this study cannot be applied to a wider patient population.