What Researchers Did
Researchers documented the case of a 26-year-old man who developed severe glans ischaemia after injecting buprenorphine into his penis.
What They Found
A 26-year-old man presented with glans pain four days after self-injecting buprenorphine, and tests revealed Enterobacter cloacae urethritis and distal penis ischaemia. After 48 hours of antibiotics showed no improvement, a 28-day multi-drug treatment including antibiotics, heparin, an antiplatelet drug, ilomedin, and hyperbaric oxygen therapy led to clinical improvement of the lesions with no functional complications.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
As a single case report, this study cannot establish general treatment guidelines or definitively prove the effectiveness of hyperbaric oxygen therapy as a standalone treatment.