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Clinical Study Pediatric nephrology (Berlin, Germany) 2010

Successful treatment of calcific uremic arteriolopathy in a pediatric dialysis patient.

Amin N, Gonzalez E, Lieber M, Salusky IB, Zaritsky JJ — Pediatric nephrology (Berlin, Germany), 2010

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported the case of a 17-year-old male paediatric dialysis patient with calcific uremic arteriolopathy (CUA) and described his treatment course.

What They Found

A 17-year-old patient developed CUA after 3 years on peritoneal dialysis. Initial treatment with sodium thiosulfate and hyperbaric oxygen was ineffective, necessitating bilateral below-the-knee amputation 5 months later. Complete resolution of CUA was observed only after converting to daily hemodialysis while continuing the other therapies.

Canadian Relevance

This study has no direct Canadian connection as it reports on a single case from outside Canada.

Study Limitations

As a single case report, the findings of this study cannot be generalized to a broader patient population.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 19885686
Year Published 2010
Journal Pediatric nephrology (Berlin, Germany)
MeSH Terms Adolescent; Antioxidants; Arterial Occlusive Diseases; Calcinosis; Combined Modality Therapy; Granulomatosis with Polyangiitis; Humans; Hyperbaric Oxygenation; Male; Renal Dialysis; Renal Insufficiency; Thiosulfates; Treatment Outcome; Uremia

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology