Successful treatment of extensive posttraumatic soft-tissue and renal infections due to Apophysomyces elegans | Canada Hyperbarics Skip to main content
Case Report Clin Infect Dis 1994

Successful treatment of extensive posttraumatic soft-tissue and renal infections due to Apophysomyces elegans

Okhuysen P, Rex J, Kapusta M, Fife C — Clin Infect Dis, 1994

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described the case of a previously healthy man who developed severe skin and kidney infections caused by the rare fungus Apophysomyces elegans after experiencing trauma.

What They Found

A multidisciplinary treatment approach, combining aggressive surgical debridement, hyperbaric oxygen therapy, and medications (liposomal amphotericin B and interferon-gamma), successfully controlled the patient's severe fungal infection. This comprehensive strategy prevented the need for kidney removal (nephrectomy).

What This Means for Canadian Patients

For Canadian patients facing severe and complex fungal infections like mucormycosis, this case suggests that a combined treatment strategy, including hyperbaric oxygen therapy, may offer a path to recovery. This approach could potentially help save affected organs and improve outcomes for those with challenging infections.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a case report, this study describes the experience of only one patient, meaning its findings cannot be broadly applied to all patients with similar infections.

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Study Details

Study Type Case Report
Category Infection
Source Pubmed
PubMed ID 7986910
Year Published 1994
Journal Clin Infect Dis
MeSH Terms Adult; Amphotericin B; Humans; Hyperbaric Oxygenation; Interferon-gamma; Kidney Diseases; Liposomes; Male; Mucorales; Mucormycosis; Soft Tissue Infections; Soft Tissue Injuries; Tomography, X-Ray Computed

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.