Successful Treatment of Refractory Bilateral Leg Ulcers With an Adsorptive Blood-Purification Device. | Canada Hyperbarics Skip to main content
Clinical Study Plastic and reconstructive surgery. Global open 2025

Successful Treatment of Refractory Bilateral Leg Ulcers With an Adsorptive Blood-Purification Device.

Iida A, Akiyama G, Matsunami K, Ogawa R — Plastic and reconstructive surgery. Global open, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case study of a 63-year-old man with refractory bilateral leg ulcers due to chronic limb-threatening ischaemia, who was treated with 20 sessions of the Rheocarna adsorptive blood-purification device alongside wound care and hyperbaric oxygen.

What They Found

The 63-year-old patient, ineligible for standard revascularization, underwent 20 Rheocarna treatment sessions. These sessions, combined with wound care and hyperbaric oxygen, led to improved circulation and ulcer healing, successfully preventing amputation.

Canadian Relevance

This study has no direct Canadian connection as the research was conducted in Japan and the device, Rheocarna, is approved there but not in Canada.

Study Limitations

A significant limitation is that this was a single case report, meaning its findings cannot be generalized without further larger-scale studies.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 40989947
Year Published 2025
Journal Plastic and reconstructive surgery. Global open

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology