Successful Treatment of Refractory Bilateral Leg Ulcers With an Adsorptive Blood-Purification Device. | Canada Hyperbarics Skip to main content
Clinical Study Plastic and reconstructive surgery. Global open 2025

Successful Treatment of Refractory Bilateral Leg Ulcers With an Adsorptive Blood-Purification Device.

Iida A, Akiyama G, Matsunami K, Ogawa R — Plastic and reconstructive surgery. Global open, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case study of a 63-year-old man with refractory bilateral leg ulcers due to chronic limb-threatening ischemia, who was treated with 20 sessions of the Rheocarna adsorptive blood-purification device alongside wound care and hyperbaric oxygen.

What They Found

The 63-year-old patient, ineligible for standard revascularization, underwent 20 Rheocarna treatment sessions. These sessions, combined with wound care and hyperbaric oxygen, led to improved circulation and ulcer healing, successfully preventing amputation.

What This Means for Canadian Patients

For Canadian patients with chronic limb-threatening ischemia and refractory ulcers who are not candidates for revascularization, this case suggests a potential alternative treatment. While Rheocarna is not yet approved in Canada, it offers a glimpse into future therapies that could prevent amputations in similar challenging cases.

Canadian Relevance

This study has no direct Canadian connection as the research was conducted in Japan and the device, Rheocarna, is approved there but not in Canada.

Study Limitations

A significant limitation is that this was a single case report, meaning its findings cannot be generalized without further larger-scale studies.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 40989947
Year Published 2025
Journal Plastic and reconstructive surgery. Global open

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.