Successful treatment of severe iatrogenic calcinosis cutis with intravenous sodium thiosulfate in a child affected by T-acute lymphoblastic leukemia | Canada Hyperbarics Skip to main content
Case Report Pediatr Dermatol 2009

Successful treatment of severe iatrogenic calcinosis cutis with intravenous sodium thiosulfate in a child affected by T-acute lymphoblastic leukemia

Raffaella C, Annapaola C, Tullio I, Angelo R, Giuseppe L, Simone C — Pediatr Dermatol, 2009

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This study describes how a 5-year-old boy with leukemia was successfully treated for severe skin calcification caused by a calcium gluconate extravasation.

What They Found

The boy developed severe calcinosis cutis on his right forearm and hand, and left leg and foot after calcium gluconate extravasation. A combination of surgical debridement, local wound care, hyperbaric oxygen therapy, and intravenous sodium thiosulfate led to complete healing of all lesions within an eight-month period. No functional or sensory problems remained after treatment.

What This Means for Canadian Patients

For Canadian patients, especially children, who develop severe skin calcification due to medical treatments, this case suggests that a multi-faceted approach including hyperbaric oxygen therapy could be effective. This offers a potential treatment pathway for a challenging condition that can arise from certain medical procedures.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a case report, this study describes the experience of only one patient, meaning its findings may not apply to all individuals with similar conditions.

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Study Details

Study Type Case Report
Category Uncategorised
Source Pubmed
PubMed ID 19706094
Year Published 2009
Journal Pediatr Dermatol
MeSH Terms Calcinosis; Calcium Gluconate; Chelating Agents; Child, Preschool; Extravasation of Diagnostic and Therapeutic Materials; Humans; Infusions, Intravenous; Male; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Skin Diseases; Thiosulfates

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.