Systemic chemotherapy using paclitaxel and carboplatin plus regional hyperthermia and hyperbaric oxygen treatment for non-small cell lung cancer with multiple pulmonary metastases: preliminary results | Canada Hyperbarics Skip to main content
Retrospective Study Int J Hyperthermia 2009

Systemic chemotherapy using paclitaxel and carboplatin plus regional hyperthermia and hyperbaric oxygen treatment for non-small cell lung cancer with multiple pulmonary metastases: preliminary results

Ohguri T, Imada H, Narisada H, Yahara K, Morioka T, Nakano K, et al. — Int J Hyperthermia, 2009

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a retrospective study on 22 patients with non-small cell lung cancer that had spread to multiple areas in the lungs, evaluating a treatment combining chemotherapy, regional hyperthermia, and hyperbaric oxygen therapy.

What They Found

The study reported that 14 (64%) of 22 patients showed an objective response to the treatment. Side effects were generally mild, with only one patient experiencing severe leucopenia/neutropenia and one patient experiencing severe pneumonitis. The median time until the disease progressed was 8 months for all patients, and 9 months for the 16 patients who received hyperbaric oxygen therapy.

What This Means for Canadian Patients

For Canadian patients with advanced non-small cell lung cancer that has spread to multiple areas in the lungs, this study suggests a combined approach of chemotherapy, hyperthermia, and hyperbaric oxygen therapy could be a promising treatment option. This multimodal strategy might offer a new avenue for managing a challenging form of lung cancer.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a retrospective case series with a small number of patients, this study's findings are preliminary and require confirmation through larger, controlled trials.

Was this summary helpful?

Study Details

Study Type Retrospective Study
Category Uncategorised
Source Pubmed
PubMed ID 19337916
Year Published 2009
Journal Int J Hyperthermia
MeSH Terms Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Hyperbaric Oxygenation; Hyperthermia, Induced; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Retrospective Studies; Treatment Outcome

Cite This Study

Share

Find a Canadian Clinic Treating Uncategorised

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.