Clinical Study Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 2024

The benefit of intravenous immune globulin in the treatment of delayed radiation myelopathy.

Naghavi S, Motahharynia A, Fatemi F, Ahmadi E, Mokhtari F, Adibi I — Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2024

View Original on PubMed PMID 37726423

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case report of a 55-year-old woman with delayed radiation myelopathy who was treated sequentially with methylprednisolone and intravenous immune globulin.

What They Found

The patient developed neurological complications 11 months post-radiotherapy, which initially resolved with methylprednisolone pulse therapy. However, residual MRI enhancement prompted intravenous immune globulin (IVIG) administration, leading to the resolution of the lesion enhancement. This suggests IVIG could be a potential therapeutic option for delayed radiation myelopathy activity.

Canadian Relevance

This study does not have a direct Canadian connection as it was not conducted in Canada, nor did it involve Canadian researchers or patients.

Study Limitations

The primary limitation of this study is its design as a single case report, which limits the generalizability of its findings and lacks a control group for comparison.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Study
Category	Radiation Injury
Source	Pubmed
PubMed ID	37726423
Year Published	2024
Journal	Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
MeSH Terms	Humans; Female; Middle Aged; Immunoglobulins, Intravenous; Radiation Injuries; Multiple Myeloma; Magnetic Resonance Imaging; Methylprednisolone; Myelitis, Transverse; Treatment Outcome; Immunologic Factors; Spinal Cord Diseases; Thoracic Vertebrae

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology