What Researchers Did
Researchers described three case studies demonstrating the development of osteoradionecrosis in the mandible from sites of periodontal disease activity following external beam radiotherapy, reviewing its pathogenesis and discussing management recommendations.
What They Found
They found that in 3 described cases, osteoradionecrosis developed in the mandible specifically from sites of periodontal disease activity after patients received external beam radiotherapy. The paper reviewed the pathogenesis of these events and proposed the use of chlorhexidine digluconate and hyperbaric oxygen for periodontal management.
Canadian Relevance
This study has no direct Canadian connection as the authors and study location are not specified as Canadian.
Study Limitations
A limitation of this study is its reliance on only three case reports, which limits the generalizability of the findings to a broader patient population.