The effect of hyperbaric oxygen therapy on hematological indices and biochemical parameters in patients with diabetic foot. | Canada Hyperbarics Skip to main content
Clinical Study Medicine 2024

The effect of hyperbaric oxygen therapy on hematological indices and biochemical parameters in patients with diabetic foot.

Ercan E, Aydin G, Erdoğan B, Özçelik F — Medicine, 2024

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers evaluated the effects of hyperbaric oxygen therapy (HBOT) on hematological indices and biochemical parameters in 103 male patients with diabetic foot treated at a single hospital.

What They Found

After HBOT, significant changes (P < .05) were observed in hematological parameters, including decreases in WBC, neutrophils, monocytes, and platelets, and increases in lymphocytes, eosinophils, MCHC, and RDW. Biochemical parameters also improved, with significant decreases in glucose, C-reactive protein, direct bilirubin, and total protein levels (P < .05). Negative correlations were noted between HBOT sessions and MCH (P = .037) and BUN (P = .037).

What This Means for Canadian Patients

For Canadian patients with diabetic foot, these findings suggest that hyperbaric oxygen therapy may offer beneficial effects on blood parameters and inflammation markers. This could potentially contribute to better overall management and healing outcomes for this complex condition.

Canadian Relevance

This study has no direct Canadian connection as it was conducted at a single hospital outside of Canada.

Study Limitations

A significant limitation of this study is its retrospective design, reliance on file records, and inclusion of only male patients from a single center.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 38518039
Year Published 2024
Journal Medicine
MeSH Terms Humans; Male; Diabetic Foot; Hyperbaric Oxygenation; Inflammation; Ischemia; Diabetes Mellitus

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.