The effect of hyperbaric oxygen therapy on ischemia-modified albumin levels in people with diabetes with foot ulcers. | Canada Hyperbarics Skip to main content
Clinical Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2014

The effect of hyperbaric oxygen therapy on ischemia-modified albumin levels in people with diabetes with foot ulcers.

Cakmak T, Metin S, Yaman H, Demirbas S, Yildiz S, Turker T, et al. — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2014

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effect of hyperbaric oxygen therapy on ischaemia-modified albumin levels in 30 diabetic patients with foot ulcers.

What They Found

Pretreatment ischaemia-modified albumin (IMA) levels were 0.010 absorbance units, but these levels did not significantly change after 10 or 20 hyperbaric oxygen sessions (p = 0.527). However, statistically significant negative correlations were observed between diabetic age and IMA levels after both the 10th (r = -0.448, p = 0.013) and 20th (r = -0.414, p = 0.023) sessions.

What This Means for Canadian Patients

Hyperbaric oxygen therapy, while beneficial for wound healing, may not directly alter ischaemia-modified albumin levels in patients with diabetic foot ulcers. Canadian patients should continue to follow their healthcare provider's recommendations for comprehensive diabetic foot ulcer management.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study's findings are limited by its small sample size and the need for further research with larger groups to confirm these results.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 25109080
Year Published 2014
Journal Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms Aged; Biomarkers; Diabetic Foot; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Serum Albumin; Serum Albumin, Human; Wound Healing

Cite This Study

Share

This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

Find a Canadian Clinic Treating Wound Care

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology