The effect of hyperbaric oxygen treatment on late radiation tissue injury after breast cancer: A case-series of 67 patients. | Canada Hyperbarics Skip to main content
Clinical Study Diving and hyperbaric medicine 2020

The effect of hyperbaric oxygen treatment on late radiation tissue injury after breast cancer: A case-series of 67 patients.

Spruijt NE, van den Berg R — Diving and hyperbaric medicine, 2020

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers analyzed a case-series of 67 breast cancer patients with late radiation tissue injury (LRTI) to assess the effect of hyperbaric oxygen treatment (HBOT).

What They Found

Of 67 patients, 57 (85%) reported at least one point improvement in their LENT-SOMA score up to 12 months after HBOT. Median pain and fibrosis scores significantly improved between the start and end of HBOT (P < 0.001), and median shoulder abduction increased significantly from 90 to 165 degrees (P = 0.001).

What This Means for Canadian Patients

Canadian breast cancer patients experiencing late radiation tissue injury may find hyperbaric oxygen treatment helpful for reducing pain, fibrosis, and swelling, and improving shoulder mobility. This treatment could offer sustained relief for up to a year after completion.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a case-series, this study lacks a control group, limiting the ability to definitively attribute improvements solely to hyperbaric oxygen treatment.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 32957121
Year Published 2020
Journal Diving and hyperbaric medicine
MeSH Terms Breast Neoplasms; Humans; Hyperbaric Oxygenation; Oxygen; Radiation Injuries; Research Design

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology