The Efficacy of Conservative Treatment of Bone Marrow Edema Syndrome: A Scoping Review of the Last Ten Years of Literature | Canada Hyperbarics Skip to main content
Review J Clin Densitom 2022

The Efficacy of Conservative Treatment of Bone Marrow Edema Syndrome: A Scoping Review of the Last Ten Years of Literature

Evola F, Compagnoni R, Pieroni A, Tassi A, Menon A, Randelli P — J Clin Densitom, 2022

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a review of studies from the last ten years to evaluate how well various non-surgical treatments work for bone marrow oedema syndrome (BMES) in the hip and knee.

What They Found

The review identified 12 studies involving a total of 351 patients. Among these, 64 patients were treated with hyperbaric oxygen (HBO) therapy across three studies. Other treatments included iloprost (34 patients), bisphosphonates (37 patients), and extracorporeal shockwave therapy (ESWT) (216 patients). ESWT studies showed that higher intensity and more sessions led to better clinical and radiological results, while iloprost improved pain in hip patients.

What This Means for Canadian Patients

For Canadian patients suffering from bone marrow oedema syndrome, this review indicates that several conservative treatments, including hyperbaric oxygen therapy, show promising results. Although treatment approaches are not yet standardised, these findings suggest potential non-surgical options for managing this condition effectively.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

A significant limitation is that the treatment of idiopathic bone marrow oedema is not standardised, making it difficult to reliably compare data from different studies.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Review
Category Systematic Reviews
Source Pubmed
PubMed ID 35987803
Year Published 2022
Journal J Clin Densitom
MeSH Terms Humans; Bone Marrow; Bone Marrow Diseases; Conservative Treatment; Diphosphonates; Edema; Iloprost; Syndrome; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology