The EXPLORE Trial: A Feasibility Study Using Fluorescence Angiography to Evaluate Perfusion in the Oxygen-Rich Environment. | Canada Hyperbarics Skip to main content
Prospective Study Surgical technology international 2016

The EXPLORE Trial: A Feasibility Study Using Fluorescence Angiography to Evaluate Perfusion in the Oxygen-Rich Environment.

Arnold JF, Roscum M — Surgical technology international, 2016

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This single-center, prospective, feasibility study included 34 subjects with various wounds to evaluate fluorescence angiography's ability to assess tissue perfusion changes during hyperbaric oxygen therapy (HBOT).

What They Found

A total of 34 subjects participated, with 22 receiving at least 10 hyperbaric oxygen therapy (HBOT) sessions. Fluorescence angiography successfully provided real-time visualization and objective assessment of changes in local tissue perfusion throughout the HBOT course.

What This Means for Canadian Patients

This study suggests that fluorescence angiography could potentially help doctors monitor how well hyperbaric oxygen therapy is improving blood flow to their wounds. This real-time feedback might lead to more personalized and effective treatment plans for complex, non-healing wounds.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or with Canadian participants.

Study Limitations

This was a single-center feasibility study with a limited sample size, which restricts the generalizability of its findings.

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Study Details

Study Type Prospective Study
Category Wound Care
Source Pubmed
PubMed ID 27728941
Year Published 2016
Journal Surgical technology international
MeSH Terms Chronic Disease; Feasibility Studies; Fluorescein Angiography; Humans; Hyperbaric Oxygenation; Oxygen; Prospective Studies; Wound Healing

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.