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Review Advances in experimental medicine and biology 2021

The Role of Hyperbaric Oxygen Treatment for COVID-19: A Review.

Paganini M, Bosco G, Perozzo FAG, Kohlscheen E, Sonda R, Bassetto F, et al. — Advances in experimental medicine and biology, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed existing literature on the role of hyperbaric oxygen treatment for COVID-19 patients.

What They Found

The review found that few COVID-19 patients globally have been successfully treated with hyperbaric oxygen (HBO) therapy. While some less severe patients exposed to HBO reportedly avoided intubation and experienced rapid symptom resolution, the existing case descriptions show large variability in treatment protocols and exposure frequency.

What This Means for Canadian Patients

Currently, there is limited and variable evidence regarding the effectiveness of hyperbaric oxygen therapy for COVID-19 patients. Canadian patients should rely on established treatments and consult their healthcare providers for appropriate care, as HBO therapy is not a standard treatment for COVID-19.

Canadian Relevance

This review did not include any specific Canadian studies or data, therefore, direct Canadian relevance is not established.

Study Limitations

A key limitation is the scarcity of robust clinical trials and the significant variability in protocols observed across the few existing case descriptions of hyperbaric oxygen treatment for COVID-19.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Review
Category COVID-19 / Long COVID
Source Pubmed
PubMed ID 32696443
Year Published 2021
Journal Advances in experimental medicine and biology
MeSH Terms COVID-19; Humans; Hyperbaric Oxygenation; Oxygen; SARS-CoV-2; COVID-19 Drug Treatment

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This study relates to Long COVID. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology