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Cohort Study Diving Hyperb Med 2024

The role of hyperbaric oxygen treatment in the management of spondylodiscitis

Canarslan Demir K, Turgut B, Sariyerli Dursun G, Konyalioğlu F, Zaman T — Diving Hyperb Med, 2024

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Turkish military hospital physicians reviewed 25 patients with spondylodiscitis (infection of the spine and discs) who were treated with HBOT plus targeted antibiotics over a six-year period, tracking pain, inflammation, and recurrence.

What They Found

Pain scores dropped from a median of 8/10 to 3/10 (P < 0.001) after treatment. Inflammation markers fell significantly: C-reactive protein dropped from 22.3 to 6.8 mg/L (P = 0.002). At a median follow-up of 48 months, no patients had persistent or recurring spondylodiscitis. HBOT was given at 2.43 ATA for 120 minutes per session, 5 days per week, for 30 total sessions.

What This Means for Canadian Patients

Spinal infection is a serious and sometimes treatment-resistant condition. For Canadians who do not fully respond to antibiotics alone, HBOT as an add-on therapy may provide meaningful pain relief and reduce the risk of the infection coming back. This is particularly relevant for post-surgical spinal infections.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The small sample of 25 patients with no control group makes it impossible to separate the benefits of HBOT from those of the antibiotics alone.

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Study Details

Study Type Cohort Study
Category Uncategorised
Source Pubmed
PubMed ID 39288919
Year Published 2024
Journal Diving Hyperb Med
MeSH Terms Humans; Hyperbaric Oxygenation; Discitis; Male; Retrospective Studies; Female; Middle Aged; C-Reactive Protein; Aged; Anti-Bacterial Agents; Combined Modality Therapy; Recurrence; Treatment Outcome; Leukocyte Count; Adult; Pain Measurement

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.