What Researchers Did
Researchers reviewed experimental studies, both lab and animal research plus a limited number of clinical trials, examining whether HBOT could make standard glioma (brain cancer) treatment more effective.
What They Found
Glioma tumours are naturally low in oxygen (hypoxic), which makes them more resistant to radiation and chemotherapy. HBOT may temporarily raise oxygen levels inside tumours, potentially reducing that resistance. However, the review found no consistent clinical evidence proving HBOT improves survival in glioma patients, with only preclinical (animal/lab) studies showing clear promise.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
This is a narrative review of mostly preclinical studies, so conclusions cannot be applied directly to human patients without randomised clinical trial evidence.