What Researchers Did
Researchers reported three cases of clinically significant inaccurate carboxyhemoglobin measurements, including false negatives and a false positive.
What They Found
They found two cases of false negative carboxyhemoglobin (COHb) measurements in patients with carbon monoxide (CO) poisoning, where initial readings were 1.8% and 2% but later confirmed to be 20.1% and 17% respectively. Additionally, one case showed a false positive COHb of 7.1% in a non-smoking patient without CO exposure.
Canadian Relevance
This study has no direct Canadian connection as indicated by the metadata.
Study Limitations
A key limitation is that this study is a case series of only three patients, limiting the generalizability of its findings.