Tissue-engineered skin in the healing of wound stumps from limb amputations secondary to purpura fulminans. | Canada Hyperbarics Skip to main content
Clinical Study Pediatric dermatology 2003

Tissue-engineered skin in the healing of wound stumps from limb amputations secondary to purpura fulminans.

Greenberg JE, Falabella AF, Bello YM, Schachner LA — Pediatric dermatology, 2003

View Original on PubMed PMID 12657020
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers applied tissue-engineered skin to the chronic, nonhealing amputation stump ulcers of a 10-month-old girl with purpura fulminans.

What They Found

In a 10-month-old girl with nonhealing amputation stumps, tissue-engineered skin induced rapid healing of her chronic ulcers. This treatment also provided substantial pain relief, suggesting a potential benefit for similar cases in children.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation of this study is that it reports on a single case, limiting the generalizability of the findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 12657020
Year Published 2003
Journal Pediatric dermatology
MeSH Terms Amputation, Surgical; Amputation Stumps; Female; Follow-Up Studies; Graft Survival; Humans; IgA Vasculitis; Infant; Lower Extremity; Necrosis; Risk Assessment; Skin Transplantation; Skin, Artificial; Tissue Engineering; Wound Healing

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology