What Researchers Did
Researchers applied topical insulin as an add-on therapy to resistant leg ulcers in a male patient with prolidase deficiency after standard treatments failed.
What They Found
The patient, who had suffered from resistant leg ulcers for 35 years due to prolidase deficiency, showed clinical improvement after topical insulin application. This suggests topical insulin has potential as a supplementary treatment for such difficult-to-treat ulcers.
Canadian Relevance
This study has no direct Canadian connection as it was conducted outside of Canada.
Study Limitations
As a single case report, the findings cannot be generalized to a larger patient population and require further investigation.