What Researchers Did
Researchers systematically reviewed literature on topical oxygen therapy (TOT) and micro/nanobubbles (MNBs) for wound healing and tissue oxygenation, and analyzed their own MNB generating technology.
What They Found
The review identified 87 articles, with 52 meeting inclusion criteria (12 on micro/nanobubbles and 40 on topical oxygen therapy). They found that micro/nanobubbles, ranging from 100 μm to less than 1 μm, offer a new and stable mode of oxygen delivery to wounds. The efficacy of existing topical oxygen therapies, however, has yet to be fully substantiated.
What This Means for Canadian Patients
This review suggests that micro/nanobubbles could represent a novel approach to improve oxygen delivery for poorly healing wounds. If proven effective in future studies, this technology might offer a new treatment option for Canadian patients suffering from chronic wounds.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
As a literature review, this study's findings are dependent on the quality and potential biases of the included articles, and it does not present new primary clinical data.