Topical oxygen treatment relieves pain from hard-to-heal leg ulcers and improves healing: a case report. | Canada Hyperbarics Skip to main content
Case Study Journal of wound care 2021

Topical oxygen treatment relieves pain from hard-to-heal leg ulcers and improves healing: a case report.

Palin L, Nordgren M, Lingemark A, Jebril W, Wikstrom JD — Journal of wound care, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on a single patient with type 1 diabetes and a painful, hard-to-heal lower leg ulcer that was treated with topical continuous oxygen therapy (TCOT) after failing standard treatments.

What They Found

Within one week of starting TCOT, the patient spontaneously stopped taking all three of their analgesics due to complete pain relief. After 2.5 months of treatment, the patient's ulcer healed completely, with no reported adverse effects.

Canadian Relevance

This study has no direct Canadian connection as it is a case report from outside Canada.

Study Limitations

As a case report, this study's findings are based on a single patient, limiting the generalizability of the results to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Case Study
Category Wound Care
Source Pubmed
PubMed ID 33729843
Year Published 2021
Journal Journal of wound care
MeSH Terms Aged; Bandages; Diabetes Mellitus, Type 1; Diabetic Foot; Humans; Leg Ulcer; Male; Oxygen; Pain; Wound Healing

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology