Topical oxygen treatment relieves pain from hard-to-heal leg ulcers and improves healing: a case series. | Canada Hyperbarics Skip to main content
Retrospective Study Journal of wound care 2022

Topical oxygen treatment relieves pain from hard-to-heal leg ulcers and improves healing: a case series.

Jebril W, Nowak M, Palin L, Nordgren M, Bachar-Wikstrom E, Wikstrom JD — Journal of wound care, 2022

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a retrospective study on 20 patients, 17 of whom had painful hard-to-heal leg ulcers, to evaluate the effect of topical continuous oxygen therapy (TCOT).

What They Found

TCOT led to rapid and substantial pain alleviation in 13 (76%) of the 17 patients with painful ulcers. Additionally, eight (40%) of the total 20 patients experienced complete wound healing with TCOT.

What This Means for Canadian Patients

Topical continuous oxygen therapy (TCOT) could offer a new, less invasive option for managing pain and promoting healing in hard-to-heal leg ulcers. This approach may be more accessible than hyperbaric oxygen therapy, potentially improving quality of life for patients suffering from chronic wounds.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a retrospective case series with a small sample size, the study lacks a control group and generalizability.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Retrospective Study
Category Wound Care
Source Pubmed
PubMed ID 35077209
Year Published 2022
Journal Journal of wound care
MeSH Terms Humans; Leg Ulcer; Oxygen; Pain; Retrospective Studies; Wound Healing

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology