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RCT BMJ 1993

Treatment of acute mountain sickness by simulated descent: a randomised controlled trial

Bärtsch P, Merki B, Hofstetter D, Maggiorini M, Kayser B, Oelz O — BMJ, 1993

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomized controlled trial to evaluate if a portable hyperbaric chamber could effectively treat acute mountain sickness in climbers at high altitude.

What They Found

One hour of treatment in a portable hyperbaric chamber at 193 mbar caused greater short-term relief of acute mountain sickness symptoms compared to a control treatment or bed rest. However, during the 12-hour follow-up, symptom scores improved in all groups with no significant differences, and analgesic intake was similar (58-80% of subjects in each group).

What This Means for Canadian Patients

For Canadians who experience acute mountain sickness, this study suggests that a portable hyperbaric chamber could offer quick, temporary relief of symptoms. However, the benefits of this pressurization treatment appear to be short-lived, meaning sustained improvement may require other interventions or continued descent.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The study found that the short-term symptom improvement from pressurization did not translate into beneficial long-term effects.

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Study Details

Study Type RCT
Category Decompression Sickness
Source Pubmed
PubMed ID 8495155
Year Published 1993
Journal BMJ
MeSH Terms Acute Disease; Adolescent; Adult; Altitude Sickness; Atmosphere Exposure Chambers; Decompression; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Mountaineering

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.