What Researchers Did
Researchers investigated how hyperbaric oxygen therapy affected gut bacteria and intestinal damage in mice with severe burns.
What They Found
Mice receiving twice-daily hyperbaric oxygen treatments (100% oxygen at 2.4 ATA for 1.5 or 2 hours) had fewer mesenteric bacterial colonies and showed less intestinal damage. However, three treatments within 24 hours led to seizures, death, and an increase in bacterial colonies. Hyperbaric oxygen therapy did not affect metabolic acidosis or lung neutrophil deposition.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
This study was conducted on mice, so its findings may not directly translate to human burn patients.