What Researchers Did
Researchers performed angiography on 51 patients with various cancers to observe if angiotensin II-induced high blood pressure could increase blood flow to tumours.
What They Found
They observed that increased tumour blood flow under angiotensin II-induced high blood pressure resulted from tumour blood vessels not responding to angiotensin II. Angiographic findings showed increased tumour vascularity in 40 (78.4%) of the 51 patients. The study suggested that this increased tumour blood flow, by potentially raising tumour oxygen levels, could be useful in hyperbaric oxygenation radiotherapy.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
This 1986 observational study only suggested a theoretical possibility for hyperbaric oxygenation radiotherapy based on an assumption of increased tumour oxygen, without directly testing HBOT or its clinical outcomes.