Clinical Study The British journal of radiology 1977

Tumour regression as a guide to prognosis: a study with experimental animals.

Denekamp J — The British journal of radiology, 1977

View Original on PubMed PMID 870132

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the relationship between tumour shrinkage during X-ray therapy and local tumour control in mice with mammary carcinomas.

What They Found

A significant correlation was observed between tumour shrinkage during treatment and local control at 150 days for three out of four fractionated X-ray schedules. A weaker correlation was found for shrinkage within a week after single doses and for one specific fractionated schedule (9F/18 days).

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

This study was conducted in experimental animals (mice) and may not directly translate to human clinical outcomes.

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Study Details

Study Type	Clinical Study
Category	Radiation Injury
Source	Pubmed
PubMed ID	870132
Year Published	1977
Journal	The British journal of radiology
MeSH Terms	Animals; Dose-Response Relationship, Radiation; Humans; Hyperbaric Oxygenation; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasm Recurrence, Local; Neoplasm Transplantation; Radiation Tolerance

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology