Use of Hyperbaric Oxygen in Patients with Necrotizing Soft Tissue Infections: A Scandinavian Multicenter, Prospective, Observational Cohort | Canada Hyperbarics Skip to main content
Cohort Study Infect Dis Ther 2025

Use of Hyperbaric Oxygen in Patients with Necrotizing Soft Tissue Infections: A Scandinavian Multicenter, Prospective, Observational Cohort

Hyldegaard O, Nekludov M, Arnell P, Nedrebø T, Karlsson Y, Madsen M, et al. — Infect Dis Ther, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers observed 409 patients with severe necrotizing soft tissue infections in Scandinavia to understand how hyperbaric oxygen therapy was used as an additional treatment.

What They Found

Out of 409 patients with necrotizing soft tissue infections, 402 (98.3%) were admitted to the ICU. Most patients, 329, received hyperbaric oxygen therapy, with the first treatment typically given 4.3 hours after arriving at a specialized hospital. Patients who received hyperbaric oxygen therapy generally had less severe underlying conditions and lower illness severity scores.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The study acknowledges potential selection bias because not all severely ill patients could receive hyperbaric oxygen therapy due to their condition or treatment availability.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Cohort Study
Category Infection
Source Pubmed
PubMed ID 40613866
Year Published 2025
Journal Infect Dis Ther

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 16, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology