Xanthogranuloma in the heavily irradiated low neck in a patient with head and neck cancer. | Canada Hyperbarics Skip to main content
Clinical Study Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 2016

Xanthogranuloma in the heavily irradiated low neck in a patient with head and neck cancer.

Singer L, Calkins SM, Horvai AE, Ryan WR, Yom SS — Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2016

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported a case of xanthogranuloma in the heavily irradiated low neck of a patient treated for oropharyngeal squamous cell carcinoma.

What They Found

They found that a patient treated for oropharyngeal squamous cell carcinoma with chemoradiation and hyperthermia developed an in-field cutaneous lesion in the low neck at eight-month follow-up. Biopsy confirmed xanthogranuloma, and after complete resection, the patient remained free of malignancy but experienced wound healing difficulties that resolved with specialized care.

Canadian Relevance

This study has no direct Canadian connection as it is a single case report from a non-Canadian institution.

Study Limitations

As a single case report, the findings of this study cannot be generalized to a broader patient population.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 27009318
Year Published 2016
Journal Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
MeSH Terms Biopsy; Carcinoma, Squamous Cell; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Necrobiotic Xanthogranuloma; Radiation Injuries; Skin; Squamous Cell Carcinoma of Head and Neck; Time Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology