Research Insights
HBOT Publication Trends: What the Literature Shows
9,401 hyperbaric oxygen therapy studies were indexed from PubMed between 2000 and 2025. Indexing peaked in 2025 with 631 studies.
This measures research activity, not effectiveness. A rising number of published studies means a topic is being investigated more; it does not mean outcomes have improved or that HBOT is appropriate for any particular patient. Counts reflect studies indexed in our database, which draws from PubMed.
Studies indexed per year, 2000-2025
2000
229
2001
204
2002
230
2003
235
2004
240
2005
249
2006
272
2007
300
2008
308
2009
280
2010
310
2011
347
2012
352
2013
373
2014
375
2015
426
2016
431
2017
387
2018
428
2019
428
2020
467
2021
491
2022
434
2023
453
2024
521
2025
631
Data generated June 27, 2026; updated weekly. How this data is produced.