[Xingnao Kaiqiao acupuncture on promoting wake-up of vegetative state after brain injury]. | Canada Hyperbarics Skip to main content
RCT Zhongguo Zhen Jiu 2021

[Xingnao Kaiqiao acupuncture on promoting wake-up of vegetative state after brain injury].

Bao Y, Zhang F, Li Q, Liu M, Cheng X, Zhang Y, et al. — Zhongguo Zhen Jiu, 2021

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers studied 100 patients in a vegetative state after brain injury to see if adding Xingnao Kaiqiao acupuncture to a regimen of rehabilitation and hyperbaric oxygen therapy (HBOT) improved their recovery compared to rehabilitation and HBOT alone.

What They Found

After 30 days, both groups showed improved Glasgow Coma Scale (GCS) and Coma Recovery Scale-Revised (CRS-R) scores compared to before treatment. The group receiving acupuncture in addition to rehabilitation and HBOT had significantly higher scores and a higher wake-up rate of 16.7% (8/48) compared to 12.0% (6/50) in the group receiving only rehabilitation and HBOT.

Canadian Relevance

No direct Canadian connection identified. The study is not Canadian, and vegetative state after brain injury is not a Health Canada-recognised indication for hyperbaric oxygen therapy.

Study Limitations

The study primarily focused on the added benefit of acupuncture, and the specific hyperbaric oxygen therapy protocol used was not detailed, making it difficult to assess HBOT's independent contribution or replicate the HBOT aspect of the treatment.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 34762375
Year Published 2021
Journal Zhongguo Zhen Jiu
MeSH Terms Acupuncture Points; Acupuncture Therapy; Brain Injuries; Humans; Persistent Vegetative State

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: June 8, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology