A case report of childhood acute lymphoblastic leukemia with leukoencephalopathy that responded to oxygenation under hyperbaric pressure therapy | Canada Hyperbarics Skip to main content
Case Report Rinsho Ketsueki 1992

A case report of childhood acute lymphoblastic leukemia with leukoencephalopathy that responded to oxygenation under hyperbaric pressure therapy

Kanekura S, Takezaki T, Kawakami K — Rinsho Ketsueki, 1992

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described a single case where hyperbaric oxygen therapy was used to treat a 6-year-old female with acute lymphoblastic leukaemia who developed leukoencephalopathy after chemotherapy and radiation.

What They Found

After starting hyperbaric oxygen therapy, the patient's conscious disturbance gradually improved. One month later, all neurological problems resolved completely, and abnormal findings on her brain magnetic resonance imaging (MRI) also improved.

Canadian Relevance

This study was not conducted in Canada, nor does it involve Canadian authors. Leukoencephalopathy is not a Health Canada-recognised indication for hyperbaric oxygen therapy. No direct Canadian connection identified.

Study Limitations

As a single case report, these findings cannot be generalized to a larger patient population and lack a control group for comparison.

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Study Details

Study Type Case Report
Category Radiation Injury
Source Pubmed
PubMed ID 1433944
Year Published 1992
Journal Rinsho Ketsueki
MeSH Terms Child; Female; Humans; Hyperbaric Oxygenation; Leukoencephalopathy, Progressive Multifocal; Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 16, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology