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RCT The Medical journal of Australia 1985

A double-blind trial of hyperbaric oxygen in the treatment of multiple sclerosis.

Wood J, Stell R, Unsworth I, Lance JW, Skuse N — The Medical journal of Australia, 1985

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a randomized double-blind trial to assess the effectiveness of hyperbaric oxygen therapy compared to a placebo for treating multiple sclerosis.

What They Found

The trial, involving 41 patients, found no advantage of hyperbaric oxygen over a placebo gas mixture. In the oxygen group (21 patients), 8 reported improvement (2 objectively confirmed), while in the placebo group (20 patients), 7 claimed improvement (4 objectively confirmed). No benefit was observed even when considering patients with mild disease or assessing individual functional systems.

What This Means for Canadian Patients

Canadian patients with multiple sclerosis should be aware that hyperbaric oxygen therapy has not been shown to be an effective treatment. It is important to rely on therapies with proven benefits for managing the condition.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study's findings are based on a specific hyperbaric oxygen regimen and a relatively small sample size of 41 patients.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 3897808
Year Published 1985
Journal The Medical journal of Australia
MeSH Terms Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Multiple Sclerosis; Placebos; Random Allocation

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.