A Refractory Livedoid Vasculopathy Accompanied by Methylene Tetrahydrofolate Reductase Gene Polymorphism Successfully Treated with Hyperbaric Oxygen Therapy | Canada Hyperbarics Skip to main content
Case Report Ann Dermatol 2023

A Refractory Livedoid Vasculopathy Accompanied by Methylene Tetrahydrofolate Reductase Gene Polymorphism Successfully Treated with Hyperbaric Oxygen Therapy

Lee S, Lee Y, Choi E — Ann Dermatol, 2023

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on a case where hyperbaric oxygen therapy successfully treated a 63-year-old woman with severe livedoid vasculopathy that had not responded to other treatments.

What They Found

A 63-year-old female patient with refractory livedoid vasculopathy, also having an MTHFR gene polymorphism, received hyperbaric oxygen therapy at 2.0 absolute atmosphere for 120 minutes, three times a week. After 4 sessions, her painful ulcers began to heal, and after 13 sessions, the skin lesions were almost completely healed. During an eight-month follow-up, the ulcers did not recur, and her symptoms remained stable.

What This Means for Canadian Patients

For Canadian patients suffering from severe, treatment-resistant livedoid vasculopathy, this case suggests hyperbaric oxygen therapy might be a potential treatment option. It offers hope for those with painful ulcers that have not improved with standard therapies, potentially leading to wound healing and symptom stability.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This study is a single case report, which means its findings may not apply to all patients with livedoid vasculopathy.

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Study Details

Study Type Case Report
Category Wound Care
Source Pubmed
PubMed ID 37853867
Year Published 2023
Journal Ann Dermatol

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.