Review J Alzheimers Dis 2021

A review of the application of hyperbaric oxygen therapy in Alzheimer's disease

Somaa F. — J Alzheimers Dis, 2021

View Original on PubMed PMID 33935095

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a literature review of 391 articles published between 1980 and 2021 to examine the mechanisms and efficacy of hyperbaric oxygen therapy (HBOT) for Alzheimer's disease (AD).

What They Found

After reviewing 391 full-text articles from 1980-2021, the researchers found evidence from both clinical and experimental studies supporting the use of hyperbaric oxygen therapy (HBOT) for Alzheimer's disease. The review advocates for HBOT as a treatment intervention for AD, exploring its molecular and physiological mechanisms.

Canadian Relevance

This review article does not have a direct Canadian connection.

Study Limitations

A limitation is that this review synthesizes existing literature without providing new primary data or establishing a definitive long-term treatment protocol for HBOT in AD.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Review
Category	Neurological
Source	Pubmed
PubMed ID	33935095
Year Published	2021
Journal	J Alzheimers Dis

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Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology