What Researchers Did
This review article examined the Marx protocols, specifically the 30/10 protocol, for the prevention and management of osteoradionecrosis using combined surgery and hyperbaric oxygen therapy.
What They Found
The review found that the 30/10 protocol, which involves 30 hyperbaric oxygen (HBO) treatments before surgery, is crucial for managing established osteoradionecrosis. Combining HBO and surgery is essential for lasting results, with more than 95 percent of patients achieving successful cure with predictable outcomes. Severe cases, such as those extending to the inferior mandibular border or involving fistulas, often require discontinuity resection.
What This Means for Canadian Patients
Canadian patients with osteoradionecrosis might benefit from treatment plans that integrate hyperbaric oxygen therapy with surgical interventions, following protocols like the Marx 30/10 approach. This combined strategy could lead to improved and more durable outcomes for their condition.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
As a review article, this study synthesizes existing literature and does not present new primary research data or clinical trial results.